סרטונים אחרונים
RCTs did not show a clear reduction in respiratory viral infection with the use of medical/surgical masks.
There were no clear differences between the use of medical/surgical masks compared with N95/P2 respirators in healthcare workers,
when used in routine care to reduce respiratory viral infection.
Do physical measures such as hand-washing or wearing masks stop or slow down the spread of respiratory viruses?
https://www.cochranelibrary.co....m/cdsr/doi/10.1002/1
Evidence published up to October 2022.
Background
Influenza (H1N1) caused by the H1N1pdm09 virus in 2009
Severe acute respiratory syndrome (SARS) in 2003
Coronavirus disease 2019 (COVID-19)
Update of a Cochrane Review last published in 2020.
We include results from studies from the current COVID-19 pandemic.
Main results
11 new RCTs and cluster-RCTs n = 610,872
Bringing the total number of RCTs to 78
Medical/surgical masks compared to no masks
Wearing masks in the community probably makes little or no difference to the outcome of influenza‐like illness
wearing a mask may make little to no difference in how many people caught a flu-like illness/COVID-like illness
Risk ratio (RR) 0.95, (0.84 to 1.09)
9 trials, n = 276,917 participants
Moderate-certainty evidence.
Wearing masks in the community probably makes little or no difference to the outcome of laboratory-confirmed influenza/SARS-CoV-2
RR 1.01, (CI 0.72 to 1.42)
6 trials, n = 13,919
Moderate-certainty evidence
Harms were rarely measured and poorly reported
(very low-certainty evidence).
N95/P2 respirators compared to medical/surgical masks
We pooled trials comparing N95/P2 respirators with medical/surgical masks
We are very uncertain on the effects of N95/P2 respirators compared with medical/surgical masks on the outcome of clinical respiratory illness
Compared with wearing medical or surgical masks, wearing N95/P2 respirators probably makes little to no difference in how many people have confirmed flu and may make little to no difference in how many people catch a flu-like illness, or respiratory illness.
Confirmed influenza
RR 0.70, (0.45 to 1.10)
N = 7,779
Very low-certainty evidence
Influenza like illness
N95/P2 respirators compared with medical/surgical masks may be effective for ILI
RR 0.82
N= 8,407
Low-certainty evidence
The use of a N95/P2 respirators compared to medical/surgical masks
Probably makes little or no difference for laboratory-confirmed influenza infection
RR 1.10
N = 8,407
Moderate-certainty evidence
Restricting pooling to healthcare workers made no difference to the overall findings.
Harms were poorly measured and reported
Discomfort wearing medical/surgical masks or N95/P2 respirators was mentioned in several studies
Very low-certainty evidence
One new RCT
Medical/surgical masks were non-inferior to N95 respirators
N = 1,009 healthcare workers in four countries,
providing direct care to COVID-19 patients.
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US, Weekly Cumulative All-Cause Excess Deaths
https://www.usmortality.com
https://www.usmortality.com/deaths/excess-cumulative/united-states
Excess deaths 2022 (Up to December 1st) 242,224
https://www150.statcan.gc.ca/n....1/pub/71-607-x/71-60
https://www23.statcan.gc.ca/imdb/p2SV.pl?Function=getSurvey&SDDS=3233
Australian Bureau of Statistics
Provisional Mortality Statistics
Reference period, Jan - Sep 2022
144,650 deaths that occurred by 30 September
19,986 (16.0%) more than the historical average.
Deaths attributed to covid, 8,160
October covid deaths, 232
Australia, September 2022
13,675 deaths (doctor certified)
1,814 were coroner referred.
UK, ONS
https://www.ons.gov.uk/peoplep....opulationandcommunit
UK Prevalence
2.61% in England (1 in 40 people)
3.94% in Wales (1 in 25 people)
4.22% in Northern Ireland (1 in 25 people)
3.26% in Scotland (1 in 30 people)
Deaths and excess deaths (W/E week 13th January 2023)
A total of 19,916 deaths were registered in the UK
20.4% above the five-year average.
Covid UK deaths
1,059 deaths involving COVID-19 registered
(up 842 on the week)
Deaths involving COVID-19 accounted for 5.3% of all deaths
UK, Office for Health Improvement
https://www.gov.uk/government/....statistics/excess-mo
Excess deaths in all age groups, (0 to 24 years)
UK, Institute and Faculty of Actuaries
https://actuaries.org.uk/news-....and-media-releases/n
Mortality rates in 2022 compare to 2019 at different ages
2022, mortality, 7.8% higher for ages 20-44
In the UK, the second half of 2022
26,300 excess deaths,
compared to 4,700 in the first half of 2022
Europe, EuroMOMO, Bulletin week 2 2023
https://www.euromomo.eu
Pooled EuroMOMO, all-cause mortalit
Elevated level of excess mortality,
overall and in all age groups.
Data from 25 European countries or subnational regions
Average levels from pre 2020
https://www.health.govt.nz/nz-....health-statistics/he
https://www.stats.govt.nz/topics/births-and-deaths
Year ended September 2021, total of 34,578 deaths
Year ended September 2022, total of 38,052 deaths
G20 Bali Leaders’ DeclarationArgentina, Australia, Brazil, Canada, China, France, Germany, Japan, India, Indonesia, Italy, Mexico, Russia, South Africa, Saudi Arabia, South Korea, Turkey, United Kingdom, United States, and European Union.https://www.consilium.europa.e....u/en/press/press-rel 22We recognize that the extensive COVID-19 immunization is a global public goodSection 23We recognize the need for strengthening local and regional health product manufacturing capacitiesWe support the WHO mRNA Vaccine Technology Transfer hubWe acknowledge the importance of shared technical standards and verification methods, to facilitate seamless international travel, interoperability, and recognizing digital solutions and non-digital solutions, including proof of vaccinations. Establishment of trusted global digital health networks,that should capitalize and build on the success of the existing standards and digital COVID-19 certificates. Part 24The COVID-19 pandemic has accelerated the transformation of the digital ecosystem and digital economy. We recognize the importance of digital transformation in reaching the SDGs. We also reaffirm the role of data for development, economic growth and social well-being. G20 updatehttps://www.g20.org/wp-content..../uploads/2022/11/202 to move towards interoperability of systems including mechanisms that validate proof of vaccination, whilst respecting the sovereignty of national health policies, and relevant national regulations such as personal data protection and data-sharing.” Indonesia’s Minister of Health Budi Gunadi Sadikin https://twitter.com/TimHinchli....ffe/status/159223282 countries should adopt digital health certificate using WHO standardsLet’s have a digital health certificate acknowledged by WHO — if you have been vaccinated or tested properly — then you can move around(next World Health Assembly in Geneva) WHO seem to be on it alreadyhttps://www.who.int/publicatio....ns/i/item/WHO-2019-n documentation of COVID-19 certificates: vaccination status: technical specifications and implementation guidance, 27 August 2021Use of scan codesKlaus Schwab, World Economic Forum (WEF) ChairAttendedFrom a doctor in AustriaIt is currently a very emotional situation in my hospital (and in general in hospitals in Austria) because many of us in the health care sector are more or less forced to get a fourth vaccine dose.
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